Summary of query kinase
Query kinase PRKACA (P17612)
Kinase group AGC
Number of inhibitors 111
Index Target Inhibitor Inhibitor 2D Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) POC Source Link
0 PRKACA CHEMBL162 BD50059889 n/a 0.9 19 n/a n/a BindingDB BindingDB
1 PRKACA Staurosporine BD00002579 n/a 0.9 n/a n/a n/a BindingDB BindingDB
2 PRKACA CHEMBL397521 BD50219803 n/a 12.9 n/a n/a n/a BindingDB BindingDB
3 PRKACA CHEMBL306580 BD50055684 n/a 130 n/a n/a n/a BindingDB BindingDB
4 PRKACA CHEMBL1077369 BD50311405 n/a 14 n/a n/a n/a BindingDB BindingDB
5 PRKACA Balanol analog 2 BD00003150 n/a 1400 n/a n/a n/a BindingDB BindingDB
6 PRKACA CHEMBL307708 BD50055677 n/a 170 n/a n/a n/a BindingDB BindingDB
7 PRKACA CHEMBL78129 BD50055670 n/a 1700 n/a n/a n/a BindingDB BindingDB
8 PRKACA cid_1245524 BD00037913 n/a 1761 n/a n/a n/a BindingDB BindingDB
9 PRKACA pyrazole-phenyl, 3 BD00025472 n/a 186 n/a n/a n/a BindingDB BindingDB
10 PRKACA Debromohymenialdisine (DBH) BD00016591 n/a 190 n/a n/a n/a BindingDB BindingDB
11 PRKACA CHEMBL80525 BD50055666 n/a 1900 n/a n/a n/a BindingDB BindingDB
12 PRKACA CHEMBL75004 BD50055681 n/a 220 n/a n/a n/a BindingDB BindingDB
13 PRKACA CHEMBL75661 BD50055672 n/a 230 n/a n/a n/a BindingDB BindingDB
14 PRKACA CHEMBL309034 BD50055676 n/a 250 n/a n/a n/a BindingDB BindingDB
15 PRKACA CHEMBL262980 BD50055679 n/a 2600 n/a n/a n/a BindingDB BindingDB
16 PRKACA Balanol analog 5 BD00003153 n/a 30 n/a n/a n/a BindingDB BindingDB
17 PRKACA CHEMBL312067 BD50055665 n/a 3000 n/a n/a n/a BindingDB BindingDB
18 PRKACA CHEMBL1077372 BD50311408 n/a 3250 n/a n/a n/a BindingDB BindingDB
19 PRKACA CHEMBL1258913 BD50327912 n/a 332 n/a n/a n/a BindingDB BindingDB
20 PRKACA Balanol analog 3 BD00003151 n/a 350 n/a n/a n/a BindingDB BindingDB
21 PRKACA CHEMBL441802 BD50055673 n/a 3600 n/a n/a n/a BindingDB BindingDB
22 PRKACA cid_5000908 BD00037203 n/a 3865 n/a n/a n/a BindingDB BindingDB
23 PRKACA CHEMBL1077370 BD50311406 n/a 390 n/a n/a n/a BindingDB BindingDB
24 PRKACA SR3677 BD00025474 n/a 3968 n/a n/a n/a BindingDB BindingDB
25 PRKACA CHEMBL1077376 BD50311410 n/a 4.9 n/a n/a n/a BindingDB BindingDB
26 PRKACA ELLIPTECINE BD50004233 n/a 4089 n/a n/a n/a BindingDB BindingDB
27 PRKACA CHEMBL306373 BD50055669 n/a 450 n/a n/a n/a BindingDB BindingDB
28 PRKACA CHEMBL306623 BD50055678 n/a 4500 n/a n/a n/a BindingDB BindingDB
29 PRKACA CHEMBL413460 BD50199310 n/a 5.3 n/a n/a n/a BindingDB BindingDB
30 PRKACA CHEMBL1077375 BD50311409 n/a 5.5 n/a n/a n/a BindingDB BindingDB
31 PRKACA Balanol analog 1 BD00003149 n/a 50 n/a n/a n/a BindingDB BindingDB
32 PRKACA CHEMBL432168 BD50055668 n/a 50 n/a n/a n/a BindingDB BindingDB
33 PRKACA CHEMBL573578 BD50298225 n/a 500 n/a n/a n/a BindingDB BindingDB
34 PRKACA CHEMBL77970 BD50055671 n/a 5200 n/a n/a n/a BindingDB BindingDB
35 PRKACA ARC-1012, 15 BD00027225 n/a 54 n/a n/a n/a BindingDB BindingDB
36 PRKACA cid_2155099 BD00037935 n/a 5457 n/a n/a n/a BindingDB BindingDB
37 PRKACA CHEMBL1077371 BD50311407 n/a 61 n/a n/a n/a BindingDB BindingDB
38 PRKACA cid_659902 BD00037886 n/a 6202 n/a n/a n/a BindingDB BindingDB
39 PRKACA pyridine-thiazole, 1 BD00025470 n/a 637 n/a n/a n/a BindingDB BindingDB
40 PRKACA CHEMBL323556 BD50216682 n/a 6641 n/a n/a n/a BindingDB BindingDB
41 PRKACA cid_3129049 BD00037924 n/a 6795 n/a n/a n/a BindingDB BindingDB
42 PRKACA pyridine-phenyl, 2 BD00025471 n/a 692 n/a n/a n/a BindingDB BindingDB
43 PRKACA Balanol analog 4 BD00003152 n/a 70 n/a n/a n/a BindingDB BindingDB
44 PRKACA CHEMBL76537 BD50055674 n/a 7500 n/a n/a n/a BindingDB BindingDB
45 PRKACA ARC-902 BD00027248 n/a 8.3 n/a n/a n/a BindingDB BindingDB
46 PRKACA CHEMBL541388 BD50196678 n/a 853 n/a n/a n/a BindingDB BindingDB
47 PRKACA cid_756681 BD00037931 n/a 8705 n/a n/a n/a BindingDB BindingDB
48 PRKACA cid_692133 BD00037908 n/a 8899 n/a n/a n/a BindingDB BindingDB
49 PRKACA cid_658219 BD00037879 n/a 8944 n/a n/a n/a BindingDB BindingDB
50 PRKACA CHEMBL308263 BD50055685 n/a 90 n/a n/a n/a BindingDB BindingDB
51 PRKACA cid_212794 BD00037933 n/a 9310 n/a n/a n/a BindingDB BindingDB
52 PRKACA cid_659763 BD00037883 n/a 9369 n/a n/a n/a BindingDB BindingDB
53 PRKACA pyrazole-phenyl, 4 BD00025473 n/a 940 n/a n/a n/a BindingDB BindingDB
54 PRKACA CHEMBL438491 BD50219805 n/a 97.3 n/a n/a n/a BindingDB BindingDB
55 PRKACA cid_820817 BD00037917 n/a 9779 n/a n/a n/a BindingDB BindingDB
56 PRKACA CHEMBL76920 BD50055682 n/a <330 n/a n/a n/a BindingDB BindingDB
57 PRKACA CHEMBL484990 BD50279338 n/a <50 n/a n/a n/a BindingDB BindingDB
58 PRKACA SB-202190 BD50104383 n/a n/a 1700 n/a n/a BindingDB BindingDB
59 PRKACA SB_202190 SB_202190 n/a n/a 1700 n/a n/a NB2008 NB2008
60 PRKACA GSK_690693 GSK_690693 n/a n/a 19 n/a n/a NB2011DRx NB2011DRx
61 PRKACA Staurosporine Staurosporine n/a n/a 19 n/a n/a NB2008 NB2008
62 PRKACA Staurosporine Staurosporine n/a n/a 19 n/a n/a NB2011DRx NB2011DRx
63 PRKACA CEP_701 CEP_701 n/a n/a 220 n/a n/a NB2011DRx NB2011DRx
64 PRKACA LY_317615 LY_317615 n/a n/a 330 n/a n/a NB2011DRx NB2011DRx
65 PRKACA cid_11409972 BD00031085 n/a n/a 3700 n/a n/a BindingDB BindingDB
66 PRKACA AST_487 AST_487 n/a n/a 3700 n/a n/a NB2008 NB2008
67 PRKACA AST_487 AST_487 n/a n/a 3700 n/a n/a NB2011DRx NB2011DRx
68 PRKACA PP_242 PP_242 n/a n/a 3700 n/a n/a NB2011DRx NB2011DRx
69 PRKACA TAE_684 TAE_684 n/a n/a 4000 n/a n/a NB2011DRx NB2011DRx
70 PRKACA LY333531 BD00017055 n/a n/a 5400 n/a n/a BindingDB BindingDB
71 PRKACA LY_333531 LY_333531 n/a n/a 5400 n/a n/a NB2008 NB2008
72 PRKACA LY_333531 LY_333531 n/a n/a 5400 n/a n/a NB2011DRx NB2011DRx
73 PRKACA A_674563 A_674563 n/a n/a 56 n/a n/a NB2011DRx NB2011DRx
74 PRKACA R406 R406 n/a n/a 600 n/a n/a NB2011DRx NB2011DRx
75 PRKACA ABT-869 BD00021079 n/a n/a 6900 n/a n/a BindingDB BindingDB
76 PRKACA ABT_869 ABT_869 n/a n/a 6900 n/a n/a NB2008 NB2008
77 PRKACA ABT_869 ABT_869 n/a n/a 6900 n/a n/a NB2011DRx NB2011DRx
78 PRKACA CHEBI:668343 BD50298227 n/a n/a 720 n/a n/a BindingDB BindingDB
79 PRKACA PKC_412 PKC_412 n/a n/a 720 n/a n/a NB2008 NB2008
80 PRKACA PKC_412 PKC_412 n/a n/a 720 n/a n/a NB2011DRx NB2011DRx
81 PRKACA CHEMBL1079040 BD50310461 1100 n/a n/a n/a n/a BindingDB BindingDB
82 PRKACA CHEMBL1079243 BD50310476 1200 n/a n/a n/a n/a BindingDB BindingDB
83 PRKACA CHEMBL1078426 BD50310462 1300 n/a n/a n/a n/a BindingDB BindingDB
84 PRKACA CHEMBL1078820 BD50310460 1400 n/a n/a n/a n/a BindingDB BindingDB
85 PRKACA CHEMBL1080970 BD50310475 1500 n/a n/a n/a n/a BindingDB BindingDB
86 PRKACA CHEMBL1080072 BD50310471 2500 n/a n/a n/a n/a BindingDB BindingDB
87 PRKACA CHEMBL1079135 BD50310474 2600 n/a n/a n/a n/a BindingDB BindingDB
88 PRKACA CHEMBL1079032 BD50310469 2800 n/a n/a n/a n/a BindingDB BindingDB
89 PRKACA CHEMBL1080071 BD50310470 34 n/a n/a n/a n/a BindingDB BindingDB
90 PRKACA CHEMBL1078930 BD50310459 380 n/a n/a n/a n/a BindingDB BindingDB
91 PRKACA CHEMBL1079294 BD50310456 540 n/a n/a n/a n/a BindingDB BindingDB
92 PRKACA CHEMBL1078929 BD50310458 600 n/a n/a n/a n/a BindingDB BindingDB
93 PRKACA CHEMBL1079295 BD50310457 720 n/a n/a n/a n/a BindingDB BindingDB
94 PRKACA CHEMBL365286 BD50168588 960 n/a n/a n/a n/a BindingDB BindingDB
95 PRKACA 796 796 n/a n/a n/a n/a n/a PDB PDB
96 PRKACA A03 A03 n/a n/a n/a n/a n/a PDB PDB
97 PRKACA A67 A67 n/a n/a n/a n/a n/a PDB PDB
98 PRKACA CAS120685_11_2 CAS120685_11_2 n/a n/a n/a n/a 34 NB2011RBC NB2011RBC
99 PRKACA CAS127243_85_0 CAS127243_85_0 n/a n/a n/a n/a 10.51 NB2011RBC NB2011RBC
100 PRKACA CAS135897_06_2 CAS135897_06_2 n/a n/a n/a n/a 44.74 NB2011RBC NB2011RBC
101 PRKACA CAS608512_97_6 CAS608512_97_6 n/a n/a n/a n/a 40.08 NB2011RBC NB2011RBC
102 PRKACA CAS62996_74_1 CAS62996_74_1 n/a n/a n/a n/a 1.93 NB2011RBC NB2011RBC
103 PRKACA CAS97161_97_2 CAS97161_97_2 n/a n/a n/a n/a 18.04 NB2011RBC NB2011RBC
104 PRKACA IPH IPH n/a n/a n/a n/a n/a PDB PDB
105 PRKACA L9L L9L n/a n/a n/a n/a n/a PDB PDB
106 PRKACA L9M L9M n/a n/a n/a n/a n/a PDB PDB
107 PRKACA L9N L9N n/a n/a n/a n/a n/a PDB PDB
108 PRKACA SKE SKE n/a n/a n/a n/a n/a PDB PDB
109 PRKACA VX6 VX6 n/a n/a n/a n/a n/a PDB PDB
110 PRKACA XFE XFE n/a n/a n/a n/a n/a PDB PDB