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Multiple sequence alignment of family kinases
Conserved residues:
Group Kinase
CAMK CASK 203
Other AURKA 133
AGC GRK6 186
CAMK PIM1 38
-YELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAK-FTSSPGLSTEDL-KREASICHMLKHPH--IVELLETYSSDGMLYMVFEFMDGA-DLCFEIVKRADAGFVYSEAVASHYMRQILEALRYCHDNNIIHRDVKPHCVLLA-SKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMAPEVVK-REPYGKPVDVWGCGVILFILLSGCLPFYGT----KERLFEGIIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERIT-----VYEALNHPWL
-FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRR----EVEIQSHLRHPN--ILRLYGYFHDATRVYLILEYAPLG-TVY-RELQ---KLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLG-SAGEL---KIADFGWSV--HAPSSRRTTLCGTLDYLPPEMIE-GRMHDEKVDLWSLGVLCYEFLVGKPPFEAN---TYQETYKRISRVEFTFPDFVT----EGARDLISRLLKHNPSQRPM-----LREVLEHPWI
F-RQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKR-IKKRKGEAMAL---NEKQILEKVNSRF--VVSLAYAYETKDALCLVLTLMNGG-DLK-FHIYH-MGQAGFPEARAVFYAAEICCGLEDLHRERIVYRDLKPENILLD-DHGHI---RISDLGLAVH-VPEGQTIKGRVGTVGYMAPEVVK-NERYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVK-EVPEEYSER--FSPQARSLCSQLLCKDPAERLGCRGGSAREVKEHPLF
-YQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDR-ISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLILERPEPVQDLF-DFIT---ERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRGEL---KLIDFGSGA--LLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHD---------EEIIRGQVFFRQRVS----SECQHLIRWCLALRPSDRPT-----FEEIQNHPWM
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