Protein Surface  Ribbon
Inhibitor A25
  ATP Location
Motifs All P-loop B3 Hinge
C-loop A-loop
Select Anchor
Summary of 2 kinases in KIF 2E9UA_A25 (CHEK1, PDB code: 2E9U, chain A)

Multiple sequence alignment of family kinases

Conserved residues:   
                            
Group      Kinase           
CAMK       CHEK1        203 
CMGC       MAPK14        24 



W-DLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCPENI-KKEICINKMLNHENVVKFYGHRRE------GNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRREFHAEPVDVWSCGIVLTAMLAGELPWDQP--SDSCQEYSDWKEKKTYLNPWKKI--D------------------------SAPLALLHKILVENPSARITIPDIKKDRW-Y
-YQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGA-DLNNIVK-CQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLAR-----HTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYF-