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Multiple sequence alignment of family kinases
Conserved residues:
Group Kinase
CAMK DAPK1 203
CMGC CDK2 4
CAMK CHEK1 9
AGC PDPK1 82
AGC PRKCA 339
-YDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRG-VSREDIEREVSILKEI-QHPNVITLHEVYENKTDVILILELVAGGELFDFLA--EKESLTEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHK---IDFGNEFKNIFGTPEFVAPEIVN-YEPLGLEADMWSIGVITYILLSGASPFLGD---TKQETLANVSAVNYEFEDEYFSNTS----------------------ALAKDFIRRLLVKDPKKRMTIQDSLQHPWI--------------
-FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPS-TAIR----EISLLKEL-NHPNIVKLLDVIHTENKLYLVFEFLHQ-DLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAI----KLADFGLARAF--GVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFF--------------
W-DLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCPEN-I-KK----EICINKML-NHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIE--PDIGMPEPDAQRFFHQLMAGVVYLHGIGITHRDIKPENLLLDERDNL----KISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRREFHAEPVDVWSCGIVLTAMLAGELPWDQP--SDSCQEYSDWKEKKTYLNPWKKI--D----------------------SAPLALLHKILVENPSARITIPDIKKDRW-Y-------------
F-KFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTR----ERDVMSRL-DHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIR--KIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHI----QITDFGTAKVLSPESKQARANSFVGTAQYVSPELLT-EKSACKSSDLWALGCIIYQLVAGLPPFRAG---NEYLIFQKIIKLEYDFPEKFF--------------------------PKARDLVEKLLVLDATKRLGCEEM------EGYGPLKAHPF---
F-NFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDV-ECTM---VEKRVLALLDKPPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQ--QVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHI----KIADFGMCKEH--MMDGVTTRTFCGTPDYIAPEIIA-YQPYGKSVDWWAYGVLLYEMLAGQPPFDGE---DEDELFQSIMEHNVSYPKSLS--------------------------KEAVSVCKGLMTKHPAKRLGC---------GPEGERDVREHAFF
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