|
|
Multiple sequence alignment of family kinases
Conserved residues:
Group Kinase
CMGC DYRK1B 203
CMGC SRPK2 81
CMGC SRPK3 79
YEIDSLIGKGSFGQVVKAYDHQTQELVAIKIIKNKKAFLNQAQI--ELRLLELMNQ--------HDTEMKYYIVHLKRHFMF----RNHLCLVFELLSY-NLYDLLR--NTHFRGVSLNLTRKLAQQLCTALLFLATPEL-SIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGTPYDLAIDMWSLGCILVEMHTGEPLFSGSNEVDQMNRIVEVLGIPPAAMLDQAPKARKYFERLPGGGWTLRRTKELRKDYQGPGTRRLQEVLGVQTGGPGGRRAGEPGHSPADYLRFQDLVLRMLEYEPAARISPLGALQHGFF-------
YHVIRKLGWGHFSTVWLCWDMQGKRFVAMKVVKSAQHYTETA--LDEIKLLKCV-RESDPSDPNKDM-----VVQLIDDFKISGMNGIHVCMVFEVLGHHLLKWIIKSNYQGL---PVRCVKSIIRQVLQGLDYLHS--KCKIIHTDIKPENILMC---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VDDAYVR
YHVVRKLGWGHFSTVWLCWDIQRKRFVALKVVKSAGHYTETA--VDEIKLLKCV-RDSDPSDPKRET-----IVQLIDDFRISGVNGVHVCMVLEVLGHQLLKWIIKSNYQGL---PVPCVKSIVRQVLHGLDYLHT--KCKIIHTDIKPENILLC---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VGDAYIR
|