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Multiple sequence alignment of family kinases
Conserved residues:
Group Kinase
CAMK MAPKAPK2 203
Other AURKA 133
CAMK CHEK2 220
CAMK MAPKAPK3 44
KVT---SQVLGLGINGKVLQIFNKRTQEKFALKMLQDCP-KAR-------R------EVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLG---PEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWI
---FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRR------EVEIQSHL-RHPNILRLYGYFHD----ATRVYLILEYAPLGTVYRELQ--KLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGEL---KIADFGWSV-HAPSSRRTTLCGTLDYLPPEMIE---GRMHDEKVDLWSLGVLCYEFLVGKPPFEAN----TYQETYKRISRVEFTFPDFVT----EGARDLISRLLKHNPSQRPMLREVLEHPWI
-YI--MSKTLGSGACGEVKLAFERKTCKKVAIKIISKRK-FAIGSAREADPALNVETEIEILKKL-NHPCIIKIKNFF-D----AEDYYIVLELMEGGELFDKVV--GNKRLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSLMRTLCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEH---RTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWL
QLS---KQVLGLGVNGKVLECFHRRTGQKCALKLLYDSP-KARQ-------------EVDHHWQASGGPHIVCILDVYENMHHGKRCLLIIMECMEGGELFSRIQERGDQAFTEREAAEIMRDIGTAIQFLHSHNIAHRDVKPENLLYTSKEKDAVLKLTDFGFAK-ETTQNALQTPCYTPYYVAPEVLG---PEKYDKSCDMWSLGVIMYILLCGFPPFYSNTGQAISPGMKRRIRLGQYGFPNPEWSEVSEDAKQLIRLLLKTDPTERLTITQFMNHPWI
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