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Multiple sequence alignment of family kinases
Conserved residues:
Group Kinase
CAMK PIM3 203
Other AURKA 133
Other AURKB 77
CAMK PIM1 38
CAMK PIM2 132
YQVGAVLGSGGFGTVYAGSRIADGLPVAVKHVVKER-VTEWGSLGGATV-PLEVVLLRKVGAAGGARG--VIRLLDWFERPDGFLLVLER-PEPAQDLFDFITERGALDEPLARRFFAQVLAAVRHCHSCGVVHRDIKDENLLVDLRSGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSATVWSLGVLLYDMVCGDIPFEQD------EEILRGRLLFRRRVSPECQQLIRWCLSLRPSERPSLDQIAAHPWM
FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRR----EVEIQSHLR----HPN--ILRLYGYFHDATRVYLILEY-APLG-TVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLG-SAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIE-GRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWI
FEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQ-IEKEGVEHQLR---REIEIQAHLH----HPN--ILRLYNYFYDRRRIYLILEY-APRG-ELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLLG-LKGELKIADFGWSVHAPSLRRKTMCGTLDYLPPEMIE-GRMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPMGAQDLISKLLRHNPSERLPLAQVSAHPWV
YQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDR-ISDWGELPNGTRVPMEVVLLKKVS----SGFSGVIRLLDWFERPDSFVLILER-PEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHD------EEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWM
YRLGPLLGKGGFGTVFAGHRLTDRLQVAIKVIPRNR-VLGWSPLSDSVTCPLEVALLWKVGAGGGHPG--VIRLLDWFETQEGFMLVLERPLPAQ-DLFDYITEKGPLGEGPSRCFFGQVVAAIQHCHSRGVVHRDIKDENILIDLRRGCAKLIDFGSGALLHDEPYTDFDGTRVYSPPEWISRHQYHALPATVWSLGILLYDMVCGDIPFERD------QEILEAELHFPAHVSPDCCALIRRCLAPKPSSRPSLEEILLDPWM
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