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Multiple sequence alignment of family kinases
Conserved residues:
Group Kinase
CMGC SRPK2 203
CMGC DYRK1B 111
CMGC SRPK3 79
YHVIRKLGWGHFSTVWLCWDMQGKRFVAMKVVKSAQHYTETA--LDEIKLLKCV-RESDPSDPNKDM-----VVQLIDDFKISGMNGIHVCMVFEVLGHHLLKWIIKSNYQGL---PVRCVKSIIRQVLQGLDYLHS--KCKIIHTDIKPENILMC---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VDDAYVR
YEIDSLIGKGSFGQVVKAYDHQTQELVAIKIIKNKKAFLNQAQI--ELRLLELMNQ--------HDTEMKYYIVHLKRHFMF----RNHLCLVFELLSY-NLYDLLR--NTHFRGVSLNLTRKLAQQLCTALLFLATPEL-SIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGTPYDLAIDMWSLGCILVEMHTGEPLFSGSNEVDQMNRIVEVLGIPPAAMLDQAPKARKYFERLPGGGWTLRRTKELRKDYQGPGTRRLQEVLGVQTGGPGGRRAGEPGHSPADYLRFQDLVLRMLEYEPAARISPLGALQHGFF-------
YHVVRKLGWGHFSTVWLCWDIQRKRFVALKVVKSAGHYTETA--VDEIKLLKCV-RDSDPSDPKRET-----IVQLIDDFRISGVNGVHVCMVLEVLGHQLLKWIIKSNYQGL---PVPCVKSIVRQVLHGLDYLHT--KCKIIHTDIKPENILLC---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VGDAYIR
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