Protein Surface  Ribbon
Inhibitor 824
  ATP Location
Motifs All P-loop B3 Hinge
C-loop A-loop
Select Anchor
Summary of 2 kinases in KIF 2X7FA_824 (TNIK, PDB code: 2X7F, chain A)

Multiple sequence alignment of family kinases

Conserved residues:   
                            
Group      Kinase           
STE        TNIK         203 
TK         FGFR1        478 



-FELVELVGNGTYGQVYKGRHV-------KTGQLAAIKVMDVTGDEEEE--IKQ--EINMLKKY-SHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGN-----------------TLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQL-DRTVGRRNT---FIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAE-GAPPLCDMHPMRALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFI
L-VLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLK-SDAT-EKDLSDLISEMEMMKMIG-KHKNIINLLGACTQ------DGPLYVIVEYASKGNLREYLQ---ARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHH--IDYYKKTTNGRLPVKWMAPEALF-----DRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCT-NELYMMMRDCWHAVPSQRPTFKQLVEDL--