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Multiple sequence alignment of family kinases
Conserved residues:
Group Kinase
Other TTK 203
CMGC CDK2 4
CAMK STK33 116
YSILKQIGSGGSSKVFQVLNEKKQ-IYAIKYVNLEEADNQTLDSYRNEIAYLNKLQQHSDKIIRLYDYEITDQYIYMVMECGNI-DLNSWLK--KKKSIDPWERKSYWKNMLEAVHTIHQHGIVHSDLKPANFLIV-DGML---------KLIDFGIANQMQPDTTSVVKDSQVGTVNYMPPEAIKDMSSSRENGKSKSKISPKSDVWSLGCILYYMTYGKTPFQQI--INQISKLHAIIDPNHEIEFPDIPE------------------------KDLQDVLKCCLKRDPKQRISIPELLAHPYV
FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKEL-N-HPNIVKLLDVIHTENKLYLVFEFLHQ-DLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAI---------KLADFGLARAF--GVPVRTYTHEVVTLWYRAPEILL----------GCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFF
YTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKSV-K-HEHIIHLEQVFETPKKMYLVMELCEDGELKEILD--RKGHFSENETRWIIQSLASAIAYLHNNDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKK-QSRSEAMLQATCGTPIYMAPEVIS-----------AHDYSQQCDIWSIGVVMYMLLRGEPPFLAS---SEEKLFELIRKGELHFENAVWNSIS----------------------DCAKSVLKQLMKVDPAHRITAKELLDNQWL
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