Kinase profiling results of kinases in KIF 3CS9A_NIL (ABL1, PDB code: 3CS9, chain A)
Template Kinase: ABL1
Template inhibitor: Nilotinib

19 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C C
MAPK14CMGC   
ABL1TK   
ABL2TK   
DDR1TK   
EPHA1TK   
EPHA3TK   
INSRTK   
CSF1RTK   
KITTK   
PDGFRATK   
PDGFRBTK   
LCKTK   
TEKTK   
TIE1TK   
NTRK2TK   
NTRK3TK   
FLT1TK   
KDRTK   
BRAFTKL   

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C
MAPK14CMGC    
ABL1TK    
ABL2TK    
CSF1RTK    
EPHA1TK    
EPHA3TK    
FLT1TK    
INSRTK    
KDRTK    
KITTK    
LCKTK    
NTRK2TK    
NTRK3TK    
PDGFRATK    
PDGFRBTK    
TEKTK    
BRAFTKL