Kinase profiling results of kinases in KIF 3CQUA_CQU (AKT1, PDB code: 3CQU, chain A)
Template Kinase: AKT1
Template inhibitor: 3cqu

 7 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
AKT1AGC
ROCK2AGC
CHEK2CAMK
CDK2CMGC
MAP4K2STE
BTKTK

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C
AKT1AGC  
ROCK2AGC  
CHEK2CAMK  
CDC2CMGC  
CDC2CMGC  
CDK2CMGC  
MAP4K2STE  
BTKTK