Kinase profiling results of kinases in KIF 3OCBA_XM1 (AKT1, PDB code: 3OCB, chain A)
Template Kinase: AKT1
Template inhibitor: XM1

 10 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
AKT1AGC 
AKT2AGC 
AKT3AGC 
ROCK1AGC 
ROCK2AGC 
GRK7AGC 
DCLK3CAMK 
MAP4K2STE 
STK3STE 
STK4STE 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C
AKT1AGC 
AKT2AGC 
AKT3AGC 
GRK7AGC 
ROCK1AGC 
ROCK2AGC 
MAP4K2STE 
STK3STE 
STK4STE