Kinase profiling results of kinases in KIF 3OW4A_SMY (AKT1, PDB code: 3OW4, chain A)
Template Kinase: AKT1
Template inhibitor: LY_317615

 3 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
AKT1AGC
AKT2AGC
AKT3AGC

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
AKT1AGC
AKT2AGC
AKT3AGC