Kinase profiling results of kinases in KIF 3E87A_G95 (AKT2, PDB code: 3E87, chain A)
Template Kinase: AKT2
Template inhibitor: AG_013736

 9 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
AKT1AGC 
AKT2AGC 
AKT3AGC 
ROCK1AGC 
ROCK2AGC 
MAPKAPK23 
PIM1CAMK 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
AKT1AGC
AKT2AGC
AKT3AGC
PRKCAAGC
ROCK1AGC
ROCK2AGC
MAPKAPK2CAMK
PIM1CAMK
CDC2CMGC
CDC2CMGC