Kinase profiling results of kinases in KIF 1MUOA_ADN (AURKA, PDB code: 1MUO, chain A)
Template Kinase: AURKA
Template inhibitor: Vidarabine

 11 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
GRK1AGC
PRKG1AGC
CASKCAMK
DAPK1CAMK
PIM1CAMK
PRKD1CAMK
CDK2CMGC
AURKAOther
EGFRTK
RETTK

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C
GRK6AGC 
PRKG1AGC 
DAPK1CAMK 
PIM1CAMK 
PRKD1CAMK 
CDK2CMGC 
AURKAOther 
EGFRTK 
RETTK