Kinase profiling results of kinases in KIF 1OL5A_ADP (AURKA, PDB code: 1OL5, chain A)
Template Kinase: AURKA
Template inhibitor: Adenosine-5'-diphosphate

 37 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
PDPK1AGC
PRKCIAGC
CASKCAMK
DAPK1CAMK
MAPKAPK23
PIM1CAMK
CHEK2CAMK
CDK2CMGC
CDK9CMGC
CSNK2A1CMGC
GSK3BCMGC
MAPK10CMGC
MAPK12CMGC
AURKAOther
NEK2Other
NEK7Other
EIF2AK2Other
PLK1Other
PLK4Other
TTKOther
OXSR1STE
STK24STE
MAP2K4STE
ABL1TK
TNK2TK
ALKTK
EGFRTK
EPHA3TK
PTK2TK
PTK2BTK
FGFR1TK
FGFR2TK
RETTK
LCKTK
ZAP70TK
IRAK4TKL

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
GRK6AGC
PDPK1AGC
PRKCIAGC
CHEK2CAMK
DAPK1CAMK
MAPKAPK2CAMK
PIM1CAMK
CDK2CMGC
CDK9CMGC
CSNK2A1CMGC
GSK3BCMGC
MAPK10CMGC
MAPK12CMGC
AURKAOther
NEK2Other
NEK7Other
PLK1Other
TTKOther
OXSR1STE
STK24STE
ABL1TK
ALKTK
EGFRTK
EPHA3TK
FGFR1TK
FGFR2TK
LCKTK
PTK2TK
PTK2BTK
RETTK
TNK2TK
ZAP70TK
IRAK4TKL