Kinase profiling results of kinases in KIF 2W1CA_L0C (AURKA, PDB code: 2W1C, chain A)
Template Kinase: AURKA
Template inhibitor: pyrazole-benzimidazole amide analogue, 9

 7 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
CDK2CMGC 
AURKAOther 
AURKBOther 
JAK2TK 
ITKTK 
BRAFTKL 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
CDC2CMGC
CDC2CMGC
CDK2CMGC
AURKAOther
AURKBOther
ITKTK
JAK2TK
BRAFTKL