Kinase profiling results of kinases in KIF 2W1DA_L0D (AURKA, PDB code: 2W1D, chain A)
Template Kinase: AURKA
Template inhibitor: AC1NTGE7

21 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
PDPK1AGC
PRKG2AGC
CHEK1CAMK
PIM1CAMK
CHEK2CAMK
CDK5CMGC
GSK3BCMGC
MAPK10CMGC
MAPK9CMGC
AURKAOther
AURKBOther
ABL1TK
ABL2TK
EGFRTK
FGFR1TK
JAK2TK
LCKTK
ITKTK
RAF1TKL

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C C
PDPK1AGC     
PRKG2AGC     
CHEK1CAMK     
CHEK2CAMK     
PIM1CAMK     
CDC2CMGC     
CDC2CMGC     
CDK5CMGC     
GSK3BCMGC     
MAPK10CMGC     
MAPK9CMGC     
AURKAOther     
AURKBOther     
WNK2Other     
ABL1TK     
ABL2TK     
EGFRTK     
FGFR1TK     
ITKTK     
JAK2TK     
LCKTK     
RAF1TKL