Kinase profiling results of kinases in KIF 2X6DA_X6D
(AURKA, PDB code: 2X6D, chain A)
Template Kinase: AURKA Template inhibitor: 6-Bromo-7-[4-(4-Chlorobenzyl)piperazin-1-Yl]-2-[4-(Morpholin-4-Ylmethyl)phenyl]-3h-Imidazo[4,5-B]pyridine
4 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45
Similarity between template inhibitor and test compounds of profiling results
Davis et al. Nature Biotechnology.29, 1046-51
<1nM
>10uM
Kinase
Kinase group
AURKA
Other
TNK2
TK
EGFR
TK
LCK
TK
Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45
