Kinase profiling results of kinases in KIF 3H0YA_48B (AURKA, PDB code: 3H0Y, chain A)
Template Kinase: AURKA
Template inhibitor: 2,4-Bisanilinopyrimidine, 5

7 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
CDK2CMGC 
AURKAOther 
AURKBOther 
PLK1Other 
ABL1TK 
EGFRTK 
NTRK1TK 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C
CDK2CMGC  
AURKAOther  
AURKBOther  
PLK1Other  
ABL1TK  
EGFRTK  
NTRK1TK