Kinase profiling results of kinases in KIF 3K5UA_PFQ (AURKA, PDB code: 3K5U, chain A)
Template Kinase: AURKA
Template inhibitor: 2-[(5,6-DIPHENYLFURO[2,3-D]PYRIMIDIN-4-YL)AMINO]ETHANOL

8 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
CHEK1CAMK
CDK2CMGC
CDK5CMGC
AURKAOther
ABL1TK
EGFRTK
FGFR1TK

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C
CHEK1CAMK  
CDC2CMGC  
CDC2CMGC  
CDK2CMGC  
CDK5CMGC  
AURKAOther  
ABL1TK  
EGFRTK  
FGFR1TK