Kinase profiling results of kinases in KIF 3MDYA_LDN (BMPR1B, PDB code: 3MDY, chain A)
Template Kinase: BMPR1B
Template inhibitor: LDN193189

 12 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
ABL1TK
JAK2TK
FYNTK
SRCTK
HCKTK
LCKTK
PTK6TK
BRAFTKL
ACVR1TKL
ACVRL1TKL
BMPR1BTKL
TGFBR1TKL

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
ABL1TK
FYNTK
HCKTK
JAK2TK
LCKTK
PTK6TK
SRCTK
ACVR1TKL
ACVRL1TKL
BRAFTKL
TGFBR1TKL