Kinase profiling results of kinases in KIF 2FB8A_215 (BRAF, PDB code: 2FB8, chain A)
Template Kinase: BRAF
Template inhibitor: SB590885

 7 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C
AURKAOther  
AURKBOther  
JAK2TK  
JAK3TK  
KDRTK  
BRAFTKL  
TGFBR1TKL  

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C
AURKAOther  
AURKBOther  
JAK2TK  
JAK3TK  
KDRTK  
BRAFTKL  
TGFBR1TKL