Kinase profiling results of kinases in KIF 2VZ6A_FEF (CAMK2A, PDB code: 2VZ6, chain A)
Template Kinase: CAMK2A
Template inhibitor: indirubin deriv. 7i

 15 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
PRKG1AGC
PRKG2AGC
CAMK2ACAMK
CHEK2CAMK
CDK2CMGC
CDK5CMGC
CSNK2A2CMGC
CLK3CMGC
AURKAOther
AURKBOther
AURKCOther
CAMKK1Other
CAMKK2Other

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C
PRKG1AGC 
PRKG2AGC 
CAMK2ACAMK 
CHEK2CAMK 
CDC2CMGC 
CDC2CMGC 
CDK2CMGC 
CDK5CMGC 
CDK6CMGC 
CDK6CMGC 
CLK3CMGC 
CSNK2A2CMGC 
AURKAOther 
AURKBOther 
AURKCOther 
CAMKK1Other 
CAMKK2Other