Kinase profiling results of kinases in KIF 3MFSA_ANP (CASK, PDB code: 3MFS, chain A)
Template Kinase: CASK
Template inhibitor: Phosphoaminophosphonic Acid-Adenylate Ester

 13 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
CASKCAMK
DAPK1CAMK
MAPKAPK23
PIM1CAMK
CHEK2CAMK
CDK2CMGC
CDK9CMGC
MAPK10CMGC
AURKAOther
PLK1Other
STK24STE

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
GRK6AGC
SGK1AGC
CHEK2CAMK
DAPK1CAMK
MAPKAPK2CAMK
PIM1CAMK
CDK2CMGC
CDK9CMGC
MAPK10CMGC
AURKAOther
PLK1Other
STK24STE