Kinase profiling results of kinases in KIF 1VYWA_292 (CDK2, PDB code: 1VYW, chain A)
Template Kinase: CDK2
Template inhibitor: PNU-292137 INHIBITOR

20 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
AKT1AGC 
PDPK1AGC 
CDK2CMGC 
CDK4CMGC 
CDK5CMGC 
GSK3ACMGC 
GSK3BCMGC 
MAPK1CMGC 
MAPK10CMGC 
MAPK8CMGC 
MAPK14CMGC 
AURKAOther 
AURKBOther 
JAK3TK 
SRCTK 
ITKTK 
MAP3K10TKL 
MAP3K11TKL 
MAP3K9TKL 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C
AKT1AGC  
PDPK1AGC  
CDC2CMGC  
CDC2CMGC  
CDK2CMGC  
CDK4CMGC  
CDK5CMGC  
GSK3ACMGC  
GSK3BCMGC  
MAPK1CMGC  
MAPK10CMGC  
MAPK14CMGC  
MAPK8CMGC  
AURKAOther  
AURKBOther  
ITKTK  
JAK3TK  
SRCTK  
MAP3K10TKL  
MAP3K11TKL  
MAP3K9TKL