Kinase profiling results of kinases in KIF 2CLXA_F18 (CDK2, PDB code: 2CLX, chain A)
Template Kinase: CDK2
Template inhibitor: 4-(3,5-Diamino-1H-pyrazol-4-ylazo)-phenol

3 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
CDK2CMGC 
CDK9CMGC 
JAK2TK 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C
CDK2CMGC  
CDK9CMGC  
JAK2TK