Kinase profiling results of kinases in KIF 2R3GA_SC9 (CDK2, PDB code: 2R3G, chain A)
Template Kinase: CDK2
Template inhibitor: 2r3j

 30 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
ROCK2AGC 
PRKCDAGC 
PRKCQAGC 
CDK2CMGC 
CDK4CMGC 
CDC2L6CMGC 
CDK8CMGC 
CLK4CMGC 
DYRK1ACMGC 
GSK3BCMGC 
MAPK3CMGC 
MAPK10CMGC 
MAPK14CMGC 
AURKAOther 
AURKBOther 
CHUKOther 
EIF2AK2Other 
PLK1Other 
ABL1TK 
DDR1TK 
PTK2TK 
JAK1TK 
JAK2TK 
JAK3TK 
METTK 
SRCTK 
LCKTK 
PTK6TK 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C C C C
PRKCAAGC       
PRKCDAGC       
PRKCQAGC       
ROCK2AGC       
CDC2CMGC       
CDC2CMGC       
CDK2CMGC       
CDK4CMGC       
CLK4CMGC       
DYRK1ACMGC       
GSK3BCMGC       
MAPK10CMGC       
MAPK14CMGC       
MAPK3CMGC       
AURKAOther       
AURKBOther       
CHUKOther       
PLK1Other       
ABL1TK       
JAK1TK       
JAK2TK       
JAK3TK       
LCKTK       
METTK       
PTK2TK       
PTK6TK       
SRCTK