Kinase profiling results of kinases in KIF 2VTSA_LZC (CDK2, PDB code: 2VTS, chain A)
Template Kinase: CDK2
Template inhibitor: DB08140

 28 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
ROCK1AGC 
ROCK2AGC 
PRKCDAGC 
PRKCQAGC 
CHEK1CAMK 
DCLK3CAMK 
PRKD1CAMK 
CDK2CMGC 
CDK4CMGC 
CDK7CMGC 
CDK9CMGC 
CDC2L5CMGC 
PCTK1CMGC 
CDK11ACMGC 
CDK11ACMGC 
CSNK2A1CMGC 
DYRK2CMGC 
HIPK4CMGC 
MAPK6CMGC 
MAPK7CMGC 
MAPK15CMGC 
MAPK8CMGC 
CHUKOther 
ERN1Other 
PLK1Other 
STK36Other 
ZAP70TK 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C
PRKCDAGC 
PRKCQAGC 
ROCK1AGC 
ROCK2AGC 
CHEK1CAMK 
PRKD1CAMK 
CDC2CMGC 
CDC2CMGC 
CDK2CMGC 
CDK4CMGC 
CDK6CMGC 
CDK6CMGC 
CDK7CMGC 
CDK9CMGC 
CSNK2A1CMGC 
DYRK2CMGC 
HIPK4CMGC 
MAPK8CMGC 
CHUKOther 
PLK1Other 
ZAP70TK