Kinase profiling results of kinases in KIF 2WIPA_P49 (CDK2, PDB code: 2WIP, chain A)
Template Kinase: CDK2
Template inhibitor: DB08355

 14 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
CDK2CMGC
CDK4CMGC
MAPK8CMGC
AURKAOther
PLK1Other
PLK2Other
PLK3Other
TTKOther
ABL1TK
FGFR1TK
JAK2TK
JAK3TK
SRCTK

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C
CDC2CMGC 
CDC2CMGC 
CDK2CMGC 
CDK4CMGC 
MAPK8CMGC 
AURKAOther 
PLK1Other 
PLK2Other 
PLK3Other 
TTKOther 
ABL1TK 
FGFR1TK 
JAK2TK 
JAK3TK 
SRCTK