Kinase profiling results of kinases in KIF 3DOGA_NNN (CDK2, PDB code: 3DOG, chain A)
Template Kinase: CDK2
Template inhibitor: NSC743927

 50 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
ROCK2AGC
RPS6KA1AGC
RPS6KA1CAMK
RPS6KA2AGC
RPS6KA2CAMK
RPS6KA6AGC
RPS6KA6CAMK
CHEK1CAMK
STK33CAMK
DAPK1CAMK
CHEK2CAMK
CDK2CMGC
CDK3CMGC
CDK4CMGC
CDK5CMGC
CDK9CMGC
PCTK1CMGC
CLK1CMGC
CLK2CMGC
CLK4CMGC
DYRK1ACMGC
DYRK1BCMGC
GSK3BCMGC
MAPK1CMGC
MAPK14CMGC
AURKAOther
AURKBOther
CAMKK2Other
CHUKOther
PLK1Other
PLK3Other
TTKOther
SLKSTE
ABL1TK
ABL2TK
TNK2TK
JAK2TK
JAK3TK
MUSKTK
FGRTK
FYNTK
SRCTK
YES1TK
HCKTK
LCKTK
LYNTK
ZAP70TK
NTRK2TK
NTRK3TK
MAP3K11TKL
MAP3K9TKL

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C C
ROCK2AGC     
RPS6KA1AGC     
RPS6KA2AGC     
RPS6KA6AGC     
CHEK1CAMK     
CHEK2CAMK     
DAPK1CAMK     
STK33CAMK     
CDC2CMGC     
CDC2CMGC     
CDK2CMGC     
CDK3CMGC     
CDK4CMGC     
CDK5CMGC     
CDK6CMGC     
CDK6CMGC     
CDK9CMGC     
CLK1CMGC     
CLK2CMGC     
CLK4CMGC     
DYRK1ACMGC     
DYRK1BCMGC     
GSK3BCMGC     
MAPK1CMGC     
MAPK14CMGC     
AURKAOther     
AURKBOther     
CAMKK2Other     
CHUKOther     
PLK1Other     
PLK3Other     
TTKOther     
SLKSTE     
ABL1TK     
ABL2TK     
FGRTK     
FYNTK     
HCKTK     
JAK2TK     
JAK3TK     
LCKTK     
LYNTK     
MUSKTK     
NTRK2TK     
NTRK3TK     
SRCTK     
TNK2TK     
YES1TK     
ZAP70TK     
MAP3K11TKL     
MAP3K9TKL