Kinase profiling results of kinases in KIF 3NUXA_3NV (CDK6, PDB code: 3NUX, chain A)
Template Kinase: CDK6
Template inhibitor: 3NV

8 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
CDK2CMGC
CDK4CMGC
GSK3BCMGC
MAPK8CMGC
MAPK9CMGC
AURKBOther
PTK6TK

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C
CDK2CMGC  
CDK4CMGC  
CDK6CMGC  
CDK6CMGC  
GSK3BCMGC  
MAPK8CMGC  
MAPK9CMGC  
AURKBOther  
PTK6TK