Kinase profiling results of kinases in KIF 2C3KA_ABO (CHEK1, PDB code: 2C3K, chain A)
Template Kinase: CHEK1
Template inhibitor: ABO

15 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
PDPK1AGC
CHEK1CAMK
MKNK2CAMK
CDK2CMGC
GSK3BCMGC
MAPK14CMGC
AURKAOther
AURKBOther
NEK2Other
SRCTK
NTRK3TK
BRAFTKL

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C
PDPK1AGC  
PRKCZAGC  
CHEK1CAMK  
MKNK2CAMK  
CDC2CMGC  
CDC2CMGC  
CDK2CMGC  
CDK6CMGC  
CDK6CMGC  
GSK3BCMGC  
MAPK14CMGC  
AURKAOther  
AURKBOther  
NEK2Other  
NTRK3TK  
SRCTK  
BRAFTKL