Kinase profiling results of kinases in KIF 2CGXA_3D3 (CHEK1, PDB code: 2CGX, chain A)
Template Kinase: CHEK1
Template inhibitor: 2-[(6-amino-7H-purin-8-yl)sulfanyl]acetamide

 2 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
CHEK1CAMK
LIMK1TKL

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
CHEK1CAMK
LIMK1TKL