Kinase profiling results of kinases in KIF 2E9UA_A25 (CHEK1, PDB code: 2E9U, chain A)
Template Kinase: CHEK1
Template inhibitor: macrocyclic inhibitor 5a

2 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
CHEK1CAMK 
MAPK14CMGC 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C
CHEK1CAMK  
MAPK14CMGC