Kinase profiling results of kinases in KIF 2GDOA_12C (CHEK1, PDB code: 2GDO, chain A)
Template Kinase: CHEK1
Template inhibitor: DB06852

 4 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
CHEK1CAMK
CDK2CMGC
MAPK14CMGC
SRCTK

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C
CHEK1CAMK  
CDK2CMGC  
MAPK14CMGC  
SRCTK