Kinase profiling results of kinases in KIF 2X8IA_X8I (CHEK1, PDB code: 2X8I, chain A)
Template Kinase: CHEK1
Template inhibitor: PI_103

 4 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
CHEK1CAMK
CDK4CMGC
CDK5CMGC
GSK3BCMGC

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C
CHEK1CAMK 
CDK4CMGC 
CDK5CMGC 
GSK3BCMGC