Kinase profiling results of kinases in KIF 3PA3A_C70 (CHEK1, PDB code: 3PA3, chain A)
Template Kinase: CHEK1
Template inhibitor: 2-(4-Chlorophenyl)-4-[(3s)-Piperidin-3-Ylamino]thieno[2,3-D]pyridazine-7-Carboxamide

11 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
CHEK1CAMK 
STK11CAMK 
NUAK1CAMK 
PRKD1CAMK 
PRKD2CAMK 
PRKD3CAMK 
CHEK2CAMK 
TSSK1BCAMK 
CDK2CMGC 
NTRK1TK 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C
CHEK1CAMK    
CHEK2CAMK    
NUAK1CAMK    
PRKD1CAMK    
PRKD2CAMK    
PRKD3CAMK    
STK11CAMK    
TSSK1BCAMK    
CDC2CMGC    
CDC2CMGC    
CDK2CMGC    
NTRK1TK