Kinase profiling results of kinases in KIF 3PA4A_C72 (CHEK1, PDB code: 3PA4, chain A)
Template Kinase: CHEK1
Template inhibitor: 2-(4-Chlorophenyl)-4-[(3s)-Piperidin-3-Ylamino]thieno[3,2-C]pyridine-7-Carboxamide

10 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
CHEK1CAMK 
STK11CAMK 
NUAK1CAMK 
PRKD1CAMK 
PRKD2CAMK 
PRKD3CAMK 
CHEK2CAMK 
TSSK1BCAMK 
MAPK14CMGC 
NTRK1TK 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C C
CHEK1CAMK     
CHEK2CAMK     
NUAK1CAMK     
PRKD1CAMK     
PRKD2CAMK     
PRKD3CAMK     
STK11CAMK     
TSSK1BCAMK     
MAPK14CMGC     
NTRK1TK