Kinase profiling results of kinases in KIF 3BEAA_IXH (CSF1R, PDB code: 3BEA, chain A)
Template Kinase: CSF1R
Template inhibitor: Pyrido[2,3-d]pyrimidin-5-one, 10

19 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C C
TNK2TK   
ALKTK   
EGFRTK   
ERBB2TK   
FGFR1TK   
IGF1RTK   
INSRTK   
JAK2TK   
JAK3TK   
METTK   
CSF1RTK   
KITTK   
PDGFRATK   
SRCTK   
HCKTK   
LCKTK   
LYNTK   
BTKTK   
NTRK1TK   

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C
ALKTK   
BTKTK   
CSF1RTK   
EGFRTK   
ERBB2TK   
FGFR1TK   
HCKTK   
IGF1RTK   
INSRTK   
JAK2TK   
JAK3TK   
KITTK   
LCKTK   
LYNTK   
METTK   
NTRK1TK   
PDGFRATK   
SRCTK   
TNK2TK