Kinase profiling results of kinases in KIF 2W4JA_ADP (DAPK1, PDB code: 2W4J, chain A)
Template Kinase: DAPK1
Template inhibitor: Adenosine-5'-diphosphate

 25 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
PDPK1AGC
RPS6KA5AGC
RPS6KA5CAMK
CASKCAMK
DAPK1CAMK
MAPKAPK23
PIM1CAMK
CHEK2CAMK
CDK2CMGC
CDK9CMGC
CSNK2A1CMGC
MAPK10CMGC
MAPK12CMGC
AURKAOther
NEK2Other
EIF2AK2Other
PLK1Other
TTKOther
STK24STE
ABL1TK
HCKTK
LCKTK
ZAP70TK

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
GRK6AGC
PDPK1AGC
RPS6KA5AGC
SGK1AGC
CHEK2CAMK
DAPK1CAMK
MAPKAPK2CAMK
PASKCAMK
PIM1CAMK
CDK2CMGC
CDK9CMGC
CSNK2A1CMGC
MAPK10CMGC
MAPK12CMGC
AURKAOther
NEK2Other
PLK1Other
TTKOther
STK24STE
ABL1TK
HCKTK
LCKTK
ZAP70TK