Kinase profiling results of kinases in KIF 2VX3A_D15 (DYRK1A, PDB code: 2VX3, chain A)
Template Kinase: DYRK1A
Template inhibitor: pyrazole-3-yl urea deriv. 15b

5 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C
CDK2CMGC  
DYRK1ACMGC  
GSK3BCMGC  
MAPK14CMGC  

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C C C
CDC2CMGC      
CDC2CMGC      
CDK2CMGC      
DYRK1ACMGC      
GSK3BCMGC      
MAPK14CMGC