Kinase profiling results of kinases in KIF 3ANRA_HRM (DYRK1A, PDB code: 3ANR, chain A)
Template Kinase: DYRK1A
Template inhibitor: HARMINE

8 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
PDPK1AGC
CDK2CMGC
CDK5CMGC
DYRK1ACMGC
DYRK2CMGC
MAPK14CMGC

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C
PDPK1AGC    
CDC2CMGC    
CDC2CMGC    
CDK2CMGC    
CDK5CMGC    
DYRK1ACMGC    
DYRK2CMGC    
DYRK3CMGC    
MAPK14CMGC