Kinase profiling results of kinases in KIF 3LZBA_ITI (EGFR, PDB code: 3LZB, chain A)
Template Kinase: EGFR
Template inhibitor: Kinome_704

13 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C
AURKAOther  
STK3STE  
PAK1STE  
EGFRTK  
ERBB2TK  
ERBB4TK  
IGF1RTK  
INSRTK  
JAK2TK  
SRCTK  
BLKTK  
LCKTK  
LYNTK  

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C
AURKAOther  
PAK1STE  
STK3STE  
BLKTK  
EGFRTK  
ERBB2TK  
ERBB4TK  
IGF1RTK  
INSRTK  
JAK2TK  
LCKTK  
LYNTK  
SRCTK