Kinase profiling results of kinases in KIF 1MQBA_ANP (EPHA2, PDB code: 1MQB, chain A)
Template Kinase: EPHA2
Template inhibitor: Phosphoaminophosphonic Acid-Adenylate Ester

 7 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
ALKTK
EPHA2TK
EPHA3TK
PTK2BTK
FGFR2TK
LCKTK
IRAK4TKL

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
ALKTK
EPHA2TK
EPHA3TK
FGFR2TK
LCKTK
PTK2BTK
IRAK4TKL