Kinase profiling results of kinases in KIF 2VX0A_7X7 (EPHB4, PDB code: 2VX0, chain A)
Template Kinase: EPHB4
Template inhibitor: 2,4-Pyrimidine derivative, 31

6 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
ALKTK 
CSKTK 
EPHB4TK 
FGFR1TK 
SRCTK 
LCKTK 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C
ALKTK 
CSKTK 
EPHB4TK 
FGFR1TK 
LCKTK 
SRCTK