Kinase profiling results of kinases in KIF 3BBTB_FMM (ERBB4, PDB code: 3BBT, chain B)
Template Kinase: ERBB4
Template inhibitor: Lapatinib

9 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
SLKSTE 
MAP2K5STE 
ABL1TK 
EGFRTK 
ERBB2TK 
ERBB3TK 
ERBB4TK 
INSRTK 
PDGFRBTK 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C
SLKSTE 
ABL1TK 
EGFRTK 
ERBB2TK 
ERBB4TK 
INSRTK 
PDGFRBTK