Kinase profiling results of kinases in KIF 1OECA_AA2 (FGFR2, PDB code: 1OEC, chain A)
Template Kinase: FGFR2
Template inhibitor: AA2

 10 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
ALKTK 
EGFRTK 
FGFR2TK 
INSRTK 
JAK1TK 
JAK2TK 
JAK3TK 
SRCTK 
LCKTK 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C
CDC2CMGC 
CDC2CMGC 
ALKTK 
EGFRTK 
FGFR2TK 
INSRTK 
JAK1TK 
JAK2TK 
JAK3TK 
LCKTK 
SRCTK