Kinase profiling results of kinases in KIF 3HNGA_8ST (FLT1, PDB code: 3HNG, chain A)
Template Kinase: FLT1
Template inhibitor: HMS3229O07

10 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C
ABL1TK  
DDR1TK  
KITTK  
PDGFRATK  
PDGFRBTK  
LCKTK  
TEKTK  
FLT1TK  
FLT4TK  
KDRTK  

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C
ABL1TK   
FLT1TK   
FLT4TK   
KDRTK   
KITTK   
LCKTK   
PDGFRATK   
PDGFRBTK   
TEKTK